PLD1 (Phospho-Thr147) Antibody MBS9407876 from MyBioSource.com

Description

Phosphatidylcholine (PC)-specific phospholipases D (PLDs; EC 3.1.4.4) catalyze the hydrolysis of PC to produce phosphatidic acid and choline. A range of agonists acting through G protein-coupled receptors and receptor tyrosine kinases stimulate this hydrolysis. PC-specific PLD activity has been implicated in numerous cellular pathways, including signal transduction, membrane trafficking, and the regulation of mitosis.Hammond S.M., J. Biol. Chem. 272:3860-3868(1997) [PubMed: 9013646].Steed P.M., FASEB J. 12:1309-1317(1998) [PubMed: 9761774].Lopez I., J. Biol. Chem. 273:12846-12852(1998) [PubMed: 9582313]

Product Specs
ItemPLD1 (Phospho-Thr147) Antibody
CompanyMyBioSource.com
Price Pricing Info Supplier Page View Company Product Page
Catalog NumberMBS9407876
Quantity0.05 ml
ApplicationsWestern Blot (WB)
Concentration1.0 mg/ml
Conjugate/TagUnconjugated
FormatRabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
PurityAntibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
ReactivityHuman
TargetPLD1
Molecular Weight112,184 Da
HostRabbit
ImmunogenThe antibody detects endogenous levels of PLD1 only when phosphorylated at threonine 147
NCBI Full Gene Namephospholipase D1, phosphatidylcholine-specific
ClonalityPolyclonal